Small-molecule fluorescent probes for specific RNA targets.
نویسندگان
چکیده
A method was developed that uses small molecules as fluorescent probes to detect specific mRNAs. In this approach, the fluorescence of fluorophore-quencher conjugates is restored by the binding of an mRNA aptamer tag to the quencher segment of the molecules. The method allows real-time detection of mRNA transcripts in vitro.
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عنوان ژورنال:
- Chemical communications
دوره 47 16 شماره
صفحات -
تاریخ انتشار 2011